| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0623 | Cla_0625 | Cla_0623 | Cla_0625 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | 0.720 |
| Cla_0623 | cysS | Cla_0623 | Cla_0630 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | cysteinyl-tRNA synthetase; Pfam matches to PF01406.10 tRNA-synt_1e, and to PF09190.2 DALR_2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.669 |
| Cla_0623 | dapA | Cla_0623 | Cla_0626 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.677 |
| Cla_0623 | ddlA | Cla_0623 | Cla_0634 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | D-alanine--D-alanine ligase; Cell wall formation. | 0.537 |
| Cla_0623 | msbA | Cla_0623 | Cla_0629 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | ABC transporter, ATP-binding protein/permease MsbA, putative; Pfam matches to PF00664.14 ABC_membrane, and to PF00005.18 ABC_tran. | 0.587 |
| Cla_0623 | murF | Cla_0623 | Cla_0637 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Pfam match to PF08245.3 Mur_ligase_M. | 0.504 |
| Cla_0623 | mviN | Cla_0623 | Cla_0631 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | Virulence factor protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.634 |
| Cla_0623 | pgsA | Cla_0623 | Cla_0624 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyltransferase; Pfam match to PF01066.12 CDP-OH_P_transf; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.804 |
| Cla_0623 | pqqL | Cla_0623 | Cla_0627 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | Peptidase, M16 family; Pfam matches to PF00675.11 Peptidase_M16, and to PF05193.12 Peptidase_M16_C. | 0.733 |
| Cla_0623 | pyrD | Cla_0623 | Cla_0628 | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.677 |
| Cla_0625 | Cla_0623 | Cla_0625 | Cla_0623 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50. | 0.720 |
| Cla_0625 | cysS | Cla_0625 | Cla_0630 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | cysteinyl-tRNA synthetase; Pfam matches to PF01406.10 tRNA-synt_1e, and to PF09190.2 DALR_2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.677 |
| Cla_0625 | dapA | Cla_0625 | Cla_0626 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.829 |
| Cla_0625 | ddlA | Cla_0625 | Cla_0634 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | D-alanine--D-alanine ligase; Cell wall formation. | 0.673 |
| Cla_0625 | msbA | Cla_0625 | Cla_0629 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | ABC transporter, ATP-binding protein/permease MsbA, putative; Pfam matches to PF00664.14 ABC_membrane, and to PF00005.18 ABC_tran. | 0.724 |
| Cla_0625 | murF | Cla_0625 | Cla_0637 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Pfam match to PF08245.3 Mur_ligase_M. | 0.667 |
| Cla_0625 | mviN | Cla_0625 | Cla_0631 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | Virulence factor protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.678 |
| Cla_0625 | pgsA | Cla_0625 | Cla_0624 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyltransferase; Pfam match to PF01066.12 CDP-OH_P_transf; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.715 |
| Cla_0625 | pqqL | Cla_0625 | Cla_0627 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | Peptidase, M16 family; Pfam matches to PF00675.11 Peptidase_M16, and to PF05193.12 Peptidase_M16_C. | 0.816 |
| Cla_0625 | pyrD | Cla_0625 | Cla_0628 | Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.820 |