Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folPDihydropteroate synthase; Pfam match to PF00809.13 Pterin_bind. (380 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam match to PF01288.11 HPPK.
 
 
 0.997
folC
Folylpolyglutamate synthase/dihydrofolate synthase; Pfam match to PF08245.3 Mur_ligase_M.
 
 0.995
folB
Dihydroneopterin aldolase.
  
 
 0.990
pabB
Para-aminobenzoate synthase component I, ADC synthase; Pfam match to PF00425.9 Chorismate_bind.
 
 
 0.976
folE
Pfam match to PF01227.13 GTP_cyclohydroI.
  
 0.964
ribF
Riboflavin kinase/FAD synthase; Pfam matches to PF06574.3 FAD_syn, and to PF01687.8 Flavokinase; Belongs to the ribF family.
     
 0.843
rppH
MutT/NUDIX family hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family.
     
 0.838
lysC
Aspartate kinase; Pfam matches to PF00696.19 AA_kinase, and to PF01842.16 ACT; Belongs to the aspartokinase family.
     
 0.830
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.829
holB
Putative DNA polymerase III delta prime subunit HolB.
  
    0.826
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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