STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (651 aa)    
Predicted Functional Partners:
lig
Pfam match to PF01068.12 DNA_ligase_A_M.
     
 0.923
lpxC
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
     
 0.876
ribF
Riboflavin kinase/FAD synthase; Pfam matches to PF06574.3 FAD_syn, and to PF01687.8 Flavokinase; Belongs to the ribF family.
 
    0.840
holB
Putative DNA polymerase III delta prime subunit HolB.
     
 0.828
folP
Dihydropteroate synthase; Pfam match to PF00809.13 Pterin_bind.
  
    0.809
por
Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR.
   
   0.807
tlyA
Ribosomal RNA large subunit methyltransferase, FtsJ family; Pfam match to PF01728.10 FtsJ.
  
    0.806
rppH
MutT/NUDIX family hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family.
       0.804
lysC
Aspartate kinase; Pfam matches to PF00696.19 AA_kinase, and to PF01842.16 ACT; Belongs to the aspartokinase family.
       0.804
hobA
Conserved hypothetical protein.
       0.804
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.