Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
pepAAminopeptidase, M17 family; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (483 aa)    
Predicted Functional Partners:
pepD
Aminoacyl-histidine dipeptidase.
   
 
 0.911
ychF
Conserved hypothetical protein, predicted GTP-binding protein (DUF933 domain protein); ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
    0.826
Cla_0679
Conserved hypothetical integral membrane protein, DedA family.
       0.825
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.825
Cla_0681
Conserved hypothetical integral membrane protein.
       0.825
rpiB
Ribose 5-phosphate isomerase B; Pfam match to PF02502.9 LacAB_rpiB.
       0.825
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.816
aspB
Aspartate aminotransferase; Pfam match to PF00155.12 Aminotran_1_2.
   
  0.814
cysK
Cysteine synthase A; Pfam match to PF00291.16 PALP; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.809
metC
Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP.
   
 
  0.802
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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