| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0687 | mqnC | Cla_0687 | Cla_0686 | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.804 |
| Cla_0687 | nssR | Cla_0687 | Cla_0689 | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | Conserved hypothetical protein, putative transcriptional regulator; Pfam match to PF00027.20 cNMP_binding. | 0.805 |
| Cla_0687 | papP | Cla_0687 | Cla_0690 | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | Conserved hypothetical protein, ABC transporter, His/Glu/Gln/Arg/opine family (permease protein); Pfam match to PF00528.13 BPD_transp_1. | 0.658 |
| Cla_0687 | recG | Cla_0687 | Cla_0688 | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | ATP-dependent DNA helicase; Pfam matches to PF00270.20 DEAD, and to PF00271.22 Helicase_C. | 0.804 |
| flgB | mqnC | Cla_1065 | Cla_0686 | Flagellar proximal rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.691 |
| mqnC | Cla_0687 | Cla_0686 | Cla_0687 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | 0.804 |
| mqnC | flgB | Cla_0686 | Cla_1065 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Flagellar proximal rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. | 0.691 |
| mqnC | mqnD | Cla_0686 | Cla_0154 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein (DUF191 domain protein); Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.979 |
| mqnC | nssR | Cla_0686 | Cla_0689 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein, putative transcriptional regulator; Pfam match to PF00027.20 cNMP_binding. | 0.804 |
| mqnC | papP | Cla_0686 | Cla_0690 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein, ABC transporter, His/Glu/Gln/Arg/opine family (permease protein); Pfam match to PF00528.13 BPD_transp_1. | 0.658 |
| mqnC | pfs | Cla_0686 | Cla_0205 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.902 |
| mqnC | recG | Cla_0686 | Cla_0688 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | ATP-dependent DNA helicase; Pfam matches to PF00270.20 DEAD, and to PF00271.22 Helicase_C. | 0.804 |
| mqnC | thiC | Cla_0686 | Cla_1025 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.678 |
| mqnC | thiG | Cla_0686 | Cla_1148 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Thiamine biosynthesis ThiGH complex, ThiG subunit; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.746 |
| mqnC | ubiA | Cla_0686 | Cla_1429 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 4-hydroxybenzoate octaprenyltranferase; Pfam match to PF01040.9 UbiA; Belongs to the UbiA prenyltransferase family. | 0.796 |
| mqnD | mqnC | Cla_0154 | Cla_0686 | Conserved hypothetical protein (DUF191 domain protein); Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.979 |
| mqnD | ubiA | Cla_0154 | Cla_1429 | Conserved hypothetical protein (DUF191 domain protein); Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 4-hydroxybenzoate octaprenyltranferase; Pfam match to PF01040.9 UbiA; Belongs to the UbiA prenyltransferase family. | 0.807 |
| nssR | Cla_0687 | Cla_0689 | Cla_0687 | Conserved hypothetical protein, putative transcriptional regulator; Pfam match to PF00027.20 cNMP_binding. | Peptidase, M16 family; Pfam match to PF05193.12 Peptidase_M16_C. | 0.805 |
| nssR | mqnC | Cla_0689 | Cla_0686 | Conserved hypothetical protein, putative transcriptional regulator; Pfam match to PF00027.20 cNMP_binding. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.804 |
| nssR | papP | Cla_0689 | Cla_0690 | Conserved hypothetical protein, putative transcriptional regulator; Pfam match to PF00027.20 cNMP_binding. | Conserved hypothetical protein, ABC transporter, His/Glu/Gln/Arg/opine family (permease protein); Pfam match to PF00528.13 BPD_transp_1. | 0.642 |