| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0727 | Cla_0730 | Cla_0727 | Cla_0730 | Conserved hypothetical protein, YceI family; Pfam match to PF04264.4 YceI; Belongs to the UPF0312 family. | Conserved hypothetical protein. | 0.445 |
| Cla_0727 | queC | Cla_0727 | Cla_0728 | Conserved hypothetical protein, YceI family; Pfam match to PF04264.4 YceI; Belongs to the UPF0312 family. | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.623 |
| Cla_0727 | ybeY | Cla_0727 | Cla_0729 | Conserved hypothetical protein, YceI family; Pfam match to PF04264.4 YceI; Belongs to the UPF0312 family. | Conserved hypothetical protein (UPF0054 domain protein); Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.470 |
| Cla_0730 | Cla_0727 | Cla_0730 | Cla_0727 | Conserved hypothetical protein. | Conserved hypothetical protein, YceI family; Pfam match to PF04264.4 YceI; Belongs to the UPF0312 family. | 0.445 |
| Cla_0730 | queC | Cla_0730 | Cla_0728 | Conserved hypothetical protein. | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.582 |
| Cla_0730 | ybeY | Cla_0730 | Cla_0729 | Conserved hypothetical protein. | Conserved hypothetical protein (UPF0054 domain protein); Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.804 |
| flaG | queC | Cla_0765 | Cla_0728 | Flagellar protein FlaG; Pfam match to PF03646.6 FlaG. | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.406 |
| nrdG | queC | Cla_0049 | Cla_0728 | Anaerobic ribonucleoside triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.635 |
| nrdG | queD | Cla_0049 | Cla_1424 | Anaerobic ribonucleoside triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Conserved hypothetical protein, putative 6-pyruvoyl tetrahydropterin synthase. | 0.790 |
| nrdG | queF | Cla_0049 | Cla_0006 | Anaerobic ribonucleoside triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Conserved hypothetical protein, putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.726 |
| queA | queC | Cla_0662 | Cla_0728 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.400 |
| queA | queF | Cla_0662 | Cla_0006 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Conserved hypothetical protein, putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.501 |
| queC | Cla_0727 | Cla_0728 | Cla_0727 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein, YceI family; Pfam match to PF04264.4 YceI; Belongs to the UPF0312 family. | 0.623 |
| queC | Cla_0730 | Cla_0728 | Cla_0730 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein. | 0.582 |
| queC | flaG | Cla_0728 | Cla_0765 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Flagellar protein FlaG; Pfam match to PF03646.6 FlaG. | 0.406 |
| queC | nrdG | Cla_0728 | Cla_0049 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Anaerobic ribonucleoside triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.635 |
| queC | queA | Cla_0728 | Cla_0662 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.400 |
| queC | queD | Cla_0728 | Cla_1424 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein, putative 6-pyruvoyl tetrahydropterin synthase. | 0.930 |
| queC | queE | Cla_0728 | Cla_1425 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.992 |
| queC | queF | Cla_0728 | Cla_0006 | Transcriptional regulator, ExsB family; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein, putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.989 |