STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysESerine O-acetyltransferase. (201 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; Pfam match to PF00291.16 PALP; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.999
cysS
cysteinyl-tRNA synthetase; Pfam matches to PF01406.10 tRNA-synt_1e, and to PF09190.2 DALR_2; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.972
sdaA
L-serine dehydratase; Pfam matches to PF03315.6 SDH_beta, and to PF03313.6 SDH_alpha; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.912
serB
3-phosphoserine phosphatase; Pfam match to PF00702.17 Hydrolase.
    
 0.851
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
     
 0.848
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.845
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.830
hom
Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh.
     
 0.817
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.814
hisS
histidyl-tRNA synthetase; Pfam match to PF00587.16 tRNA-synt_2b.
     
 0.808
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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