Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hspRTranscriptional regulator, MerR family; Pfam match to PF00376.14 MerR. (124 aa)    
Predicted Functional Partners:
cbpA
Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C.
  
 
 0.963
rpoB
DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.922
rpoC
DNA-directed RNA polymerase, beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.922
kefB
Sodium/hydrogen exchanger family protein; Pfam matches to PF00999.12 Na_H_Exchanger, and to PF02254.9 TrkA_N; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.855
Cla_0772
Conserved hypothetical protein.
       0.770
Cla_0773
Conserved hypothetical protein (DUF2018 domain protein); Pfam match to PF09442.1 DUF2018.
       0.770
Cla_0774
Conserved hypothetical protein, putative HAD superfamily hydrolase; Pfam match to PF00702.17 Hydrolase.
       0.770
Cla_0775
Conserved hypothetical protein.
       0.751
rpoD
RNA polymerase sigma 70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.716
hrcA
Heat-inducible transcription repressor.
   
 
 0.692
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.