Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htrAPeriplasmic serine protease DO; Pfam match to PF00089.17 Trypsin; Belongs to the peptidase S1C family. (472 aa)    
Predicted Functional Partners:
cprR
Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C.
  
  
 0.945
cprS
Two-component sensor histidine kinase; Pfam matches to PF00672.16 HAMP, and to PF00512.16 HisKA.
  
  
 0.907
cadF
Outer membrane fibronectin-binding protein; Pfam match to PF00691.11 OmpA.
    
 
 0.813
rep
ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase.
       0.804
peb4
Major antigenic peptide PEB-cell binding factor; Pfam match to PF00639.12 Rotamase.
     
 0.704
sodB
Superoxide dismutase (Fe); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.693
ciaB
Invasion antigen B.
      
 0.685
cbpA
Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C.
  
 
 0.674
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
       0.672
rpoD
RNA polymerase sigma 70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.670
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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