Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cprRTwo-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. (224 aa)    
Predicted Functional Partners:
cprS
Two-component sensor histidine kinase; Pfam matches to PF00672.16 HAMP, and to PF00512.16 HisKA.
 
 
 0.990
htrA
Periplasmic serine protease DO; Pfam match to PF00089.17 Trypsin; Belongs to the peptidase S1C family.
  
  
 0.945
rpoB
DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.883
rpoC
DNA-directed RNA polymerase, beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.883
Cla_0127
Two-component sensor histidine kinase; Pfam match to PF02518.17 HATPase_c.
  
   0.863
dccS
Two-component sensor histidine kinase; Pfam matches to PF00512.16 HisKA, and to PF02518.17 HATPase_c.
  
   0.860
rep
ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase.
 
     0.853
phosS
Two-component sensor histidine kinase; Pfam matches to PF00512.16 HisKA, and to PF02518.17 HATPase_c.
 
 
 0.831
lspA
Signal peptidase II, peptidase A8 family; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
      
 0.746
rpoD
RNA polymerase sigma 70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.715
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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