STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cla_0794Conserved hypothetical protein (DUF45 domain protein); Pfam match to PF01863.8 DUF45. (221 aa)    
Predicted Functional Partners:
Cla_0795
Conserved hypothetical integral membrane protein, MATE family efflux protein; Pfam matches to PF01554.9 MatE, and to PF01554.9 MatE.
  
    0.805
hypF
Transcriptional regulatory protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
  
    0.678
Cla_0793
Conserved hypothetical protein.
  
    0.678
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.541
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.524
hypC
Hydrogenase assembly chaperone HypC; Pfam match to PF01455.9 HupF_HypC.
  
    0.523
hypE
Hydrogenase expression/formation protein HypE; Pfam matches to PF00586.15 AIRS, and to PF02769.13 AIRS_C.
       0.518
hypD
Hydrogenase expression/formation protein HypD; Pfam match to PF01924.7 HypD; Belongs to the HypD family.
       0.518
hypB
Hydrogenase accessory protein HypB; Pfam match to PF02492.10 cobW.
       0.518
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.