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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ilvBAcetolactate synthase III, valine-sensitive, large subunit; Pfam matches to PF02776.9 TPP_enzyme_N, and to PF00205.13 TPP_enzyme_M. (569 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase III, valine-sensitive, small subunit; Pfam match to PF01842.16 ACT.
 
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.996
ilvD
Dihydroxyacid dehydratase; Pfam match to PF00920.12 ILVD_EDD; Belongs to the IlvD/Edd family.
 
 0.981
oorB
2-oxoglutarate:acceptor oxidoreductase, OorB subunit; Pfam match to PF02775.12 TPP_enzyme_C.
  
 
 0.966
oorA
2-oxoglutarate:acceptor oxidoreductase, OorA subunit; Pfam match to PF01855.10 POR_N.
  
 
 0.966
por
Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR.
  
 
 0.961
ilvA
Threonine dehydratase; Pfam match to PF00291.16 PALP.
  
 0.943
mez
Malate oxidoreductase; Pfam matches to PF00390.10 malic, and to PF03949.6 Malic_M.
  
 0.872
pyk
Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family.
  
 0.842
lpxD
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
     
 0.829
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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