STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Pfam matches to PF00056.14 Ldh_1_N, and to PF02866.9 Ldh_1_C; Belongs to the LDH/MDH superfamily. (298 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.982
mez
Malate oxidoreductase; Pfam matches to PF00390.10 malic, and to PF03949.6 Malic_M.
  
 0.980
oorA
2-oxoglutarate:acceptor oxidoreductase, OorA subunit; Pfam match to PF01855.10 POR_N.
  
  
 0.970
oorC
2-oxoglutarate:acceptor oxidoreductase, OorC subunit; Pfam match to PF01558.9 POR.
  
  
 0.957
por
Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR.
  
 
 0.951
pycB
Pyruvate carboxylase, subunit B; Pfam matches to PF00682.10 HMGL-like, and to PF00364.13 Biotin_lipoyl.
    
 0.949
aspB
Aspartate aminotransferase; Pfam match to PF00155.12 Aminotran_1_2.
  
 0.926
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
   
 
 0.922
mqo
Malate:quinone oxidoreductase; Pfam match to PF01266.15 DAO.
    
 0.917
atpA
ATP synthase F1 sector, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.916
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.