STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Cla_0917Outer membrane efflux protein; Pfam match to PF02321.9 OEP. (446 aa)    
Predicted Functional Partners:
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.978
macA
AcrA/AcrE family efflux protein; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.964
cmeA
RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.822
cmeB
RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran.
 
 
 0.782
cmeD
Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP.
  
   
 0.742
Cla_0842
Conserved hypothetical protein.
  
 
 0.724
ctsD
Putative type II protein secretion system D protein CtsD; Pfam match to PF00263.12 Secretin; Belongs to the bacterial secretin family.
  
  
 0.679
rdxA
Nitroreductase; Pfam match to PF00881.15 Nitroreductase.
     
 0.644
dusB
tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
      
 0.643
rpmF
Pfam match to PF01783.14 Ribosomal_L32p; Belongs to the bacterial ribosomal protein bL32 family.
      
 0.630
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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