STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rdxANitroreductase; Pfam match to PF00881.15 Nitroreductase. (202 aa)    
Predicted Functional Partners:
aas
Pfam matches to PF07690.7 MFS_1, and to PF01553.12 Acyltransferase.
   
 
 0.822
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
  
 0.699
metK
S-adenosylmethionine synthetase; Pfam matches to PF00438.11 S-AdoMet_synt_N, and to PF02772.7 S-AdoMet_synt_M; Belongs to the AdoMet synthase family.
  
  
 0.679
Cla_0917
Outer membrane efflux protein; Pfam match to PF02321.9 OEP.
     
 0.644
macA
AcrA/AcrE family efflux protein; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.636
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
       0.631
Cla_1384
Conserved hypothetical protein, putative metal-dependent membrane protease; Pfam match to PF02517.7 Abi.
  
  
 0.572
Cla_0922
Conserved hypothetical protein, putative pyridine nucleotide-disulphide oxidoreductase; Pfam match to PF00070.18 Pyr_redox.
 
 
 
 0.540
putA
Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.508
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.493
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.