STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxJPyridoxal phosphate biosynthetic protein J; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (255 aa)    
Predicted Functional Partners:
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
 
  
 0.961
pitB
Putative phosphate-transport permease PitB; Pfam match to PF01384.11 PHO4.
       0.688
Cla_0932
Ppx/GppA phosphatase family superfamily; Pfam match to PF02541.7 Ppx-GppA.
       0.630
Cla_0933
Conserved hypothetical protein, GatB/YqeY family; Pfam match to PF09424.1 YqeY.
       0.621
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.612
Cla_0934
DNA/RNA non-specific endonuclease; Pfam match to PF01223.14 Endonuclease_NS.
       0.571
Cla_0339
Conserved hypothetical protein, pyridoxamine 5'-phosphate oxidase family; Pfam match to PF01243.11 Pyridox_oxidase.
     
  0.499
fliH
Flagellar biosynthesis protein FliH; Pfam match to PF02108.7 FliH.
     
  0.499
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family.
     
 0.492
ribD
Riboflavin biosynthesis protein; Pfam match to PF00383.13 dCMP_cyt_deam_1.
     
 0.491
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.