| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbpA | dnaK | Cla_0778 | Cla_0935 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
| cbpA | groES | Cla_0778 | Cla_1035 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.761 |
| cbpA | grpE | Cla_0778 | Cla_0936 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | Co-chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of AT [...] | 0.962 |
| cbpA | hrcA | Cla_0778 | Cla_0937 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | Heat-inducible transcription repressor. | 0.856 |
| cbpA | hspR | Cla_0778 | Cla_0777 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | Transcriptional regulator, MerR family; Pfam match to PF00376.14 MerR. | 0.963 |
| cbpA | rpsB | Cla_0778 | Cla_1094 | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | Pfam match to PF00318.11 Ribosomal_S2; Belongs to the universal ribosomal protein uS2 family. | 0.410 |
| dnaJ | dnaK | Cla_0493 | Cla_0935 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.996 |
| dnaJ | groES | Cla_0493 | Cla_1035 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.855 |
| dnaJ | grpE | Cla_0493 | Cla_0936 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Co-chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of AT [...] | 0.988 |
| dnaJ | hrcA | Cla_0493 | Cla_0937 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Heat-inducible transcription repressor. | 0.700 |
| dnaJ | hspR | Cla_0493 | Cla_0777 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Transcriptional regulator, MerR family; Pfam match to PF00376.14 MerR. | 0.400 |
| dnaJ | rpsB | Cla_0493 | Cla_1094 | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Pfam match to PF00318.11 Ribosomal_S2; Belongs to the universal ribosomal protein uS2 family. | 0.410 |
| dnaK | cbpA | Cla_0935 | Cla_0778 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone-curved DNA binding protein A; Pfam matches to PF00226.22 DnaJ, and to PF01556.9 DnaJ_C. | 0.993 |
| dnaK | dnaJ | Cla_0935 | Cla_0493 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | 0.996 |
| dnaK | groES | Cla_0935 | Cla_1035 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.985 |
| dnaK | grpE | Cla_0935 | Cla_0936 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of AT [...] | 0.999 |
| dnaK | hrcA | Cla_0935 | Cla_0937 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat-inducible transcription repressor. | 0.950 |
| dnaK | hspR | Cla_0935 | Cla_0777 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Transcriptional regulator, MerR family; Pfam match to PF00376.14 MerR. | 0.557 |
| dnaK | rplA | Cla_0935 | Cla_0446 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.475 |
| dnaK | rpsB | Cla_0935 | Cla_1094 | Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Pfam match to PF00318.11 Ribosomal_S2; Belongs to the universal ribosomal protein uS2 family. | 0.712 |
