STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnrPfam match to PF00773.10 RNB; Belongs to the RNR ribonuclease family. (646 aa)    
Predicted Functional Partners:
holA
Conserved hypothetical protein; Pfam match to PF06144.4 DNA_pol3_delta.
       0.804
rppH
MutT/NUDIX family hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family.
   
 0.791
Cla_1033
NUDIX domain protein; Pfam match to PF00293.19 NUDIX.
   
 0.761
Cla_1418
Conserved hypothetical protein, probable rRNA methyltransferase, TrmH family; Pfam matches to PF08032.3 SpoU_sub_bind, and to PF00588.10 SpoU_methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
   0.736
Cla_0944
NOL1/NOP2/sun family protein; Pfam match to PF01189.8 Nol1_Nop2_Fmu; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
   0.704
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
   0.633
Cla_0945
Conserved hypothetical protein (UPF0081 domain protein); Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
     
 0.620
dprA
DNA processing protein A; Pfam match to PF02481.6 SMF.
       0.615
Cla_0947
Conserved hypothetical protein, polysaccharide deacetylase domain protein; Pfam match to PF04748.4 Polysacc_deac_2.
       0.615
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.615
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.