Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
holAConserved hypothetical protein; Pfam match to PF06144.4 DNA_pol3_delta. (321 aa)    
Predicted Functional Partners:
holB
Putative DNA polymerase III delta prime subunit HolB.
 
 
 0.994
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.991
dnaE
DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha.
   
 0.988
dnaX
DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.982
dnaQ
DNA polymerase III, epsilon subunit; Pfam match to PF00929.15 Exonuc_X-T.
    
 0.918
rnr
Pfam match to PF00773.10 RNB; Belongs to the RNR ribonuclease family.
       0.825
ybgF
Conserved hypothetical protein.
 
     0.786
Cla_1510
Conserved hypothetical protein (RDD domain protein); Pfam match to PF06271.3 RDD.
 
     0.785
Cla_0960
Conserved hypothetical lipoprotein.
 
     0.783
Cla_1216
Conserved hypothetical protein, putative ComEC/Rec2-related protein domain protein; Pfam match to PF03772.7 Competence.
 
   
 0.783
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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