| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpP | polA | Cla_1479 | Cla_1341 | ATP-dependent ClpAP/ClpXP protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.743 |
| clpP | ssb | Cla_1479 | Cla_0952 | ATP-dependent ClpAP/ClpXP protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Single-strand DNA binding protein; Pfam match to PF00436.16 SSB. | 0.824 |
| dnaE | dnaX | Cla_0892 | Cla_0470 | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.990 |
| dnaE | holB | Cla_0892 | Cla_0671 | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | Putative DNA polymerase III delta prime subunit HolB. | 0.982 |
| dnaE | polA | Cla_0892 | Cla_1341 | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.597 |
| dnaE | ssb | Cla_0892 | Cla_0952 | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | Single-strand DNA binding protein; Pfam match to PF00436.16 SSB. | 0.892 |
| dnaX | dnaE | Cla_0470 | Cla_0892 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | 0.990 |
| dnaX | holB | Cla_0470 | Cla_0671 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Putative DNA polymerase III delta prime subunit HolB. | 0.900 |
| dnaX | polA | Cla_0470 | Cla_1341 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.502 |
| dnaX | ssb | Cla_0470 | Cla_0952 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Single-strand DNA binding protein; Pfam match to PF00436.16 SSB. | 0.874 |
| holB | dnaE | Cla_0671 | Cla_0892 | Putative DNA polymerase III delta prime subunit HolB. | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | 0.982 |
| holB | dnaX | Cla_0671 | Cla_0470 | Putative DNA polymerase III delta prime subunit HolB. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.900 |
| holB | polA | Cla_0671 | Cla_1341 | Putative DNA polymerase III delta prime subunit HolB. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.562 |
| holB | ssb | Cla_0671 | Cla_0952 | Putative DNA polymerase III delta prime subunit HolB. | Single-strand DNA binding protein; Pfam match to PF00436.16 SSB. | 0.822 |
| polA | clpP | Cla_1341 | Cla_1479 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | ATP-dependent ClpAP/ClpXP protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.743 |
| polA | dnaE | Cla_1341 | Cla_0892 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, alpha chain; Pfam matches to PF02811.10 PHP, and to PF07733.3 DNA_pol3_alpha. | 0.597 |
| polA | dnaX | Cla_1341 | Cla_0470 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.502 |
| polA | holB | Cla_1341 | Cla_0671 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative DNA polymerase III delta prime subunit HolB. | 0.562 |
| polA | priA | Cla_1341 | Cla_1182 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.536 |
| polA | rpsR | Cla_1341 | Cla_0953 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.401 |