| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0926 | aroC | Cla_0926 | Cla_1493 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.416 |
| Cla_0926 | aroE | Cla_0926 | Cla_0492 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.478 |
| Cla_0926 | pabA | Cla_0926 | Cla_0985 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Para-aminobenzoate synthase component II, glutamine amidotransferase; Pfam match to PF00117.19 GATase. | 0.932 |
| Cla_0926 | pabB | Cla_0926 | Cla_0984 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Para-aminobenzoate synthase component I, ADC synthase; Pfam match to PF00425.9 Chorismate_bind. | 0.991 |
| Cla_0926 | pheA | Cla_0926 | Cla_1360 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.586 |
| Cla_0926 | trpB | Cla_0926 | Cla_1345 | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.994 |
| Cla_0983 | cmeD | Cla_0983 | Cla_0986 | Conserved hypothetical integral membrane protein, predicted permease; Pfam match to PF03547.9 Mem_trans. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.731 |
| Cla_0983 | cmeE | Cla_0983 | Cla_0987 | Conserved hypothetical integral membrane protein, predicted permease; Pfam match to PF03547.9 Mem_trans. | Membrane fusion component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.704 |
| Cla_0983 | fliP | Cla_0983 | Cla_0982 | Conserved hypothetical integral membrane protein, predicted permease; Pfam match to PF03547.9 Mem_trans. | Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. | 0.775 |
| Cla_0983 | pabA | Cla_0983 | Cla_0985 | Conserved hypothetical integral membrane protein, predicted permease; Pfam match to PF03547.9 Mem_trans. | Para-aminobenzoate synthase component II, glutamine amidotransferase; Pfam match to PF00117.19 GATase. | 0.781 |
| Cla_0983 | pabB | Cla_0983 | Cla_0984 | Conserved hypothetical integral membrane protein, predicted permease; Pfam match to PF03547.9 Mem_trans. | Para-aminobenzoate synthase component I, ADC synthase; Pfam match to PF00425.9 Chorismate_bind. | 0.818 |
| aroC | Cla_0926 | Cla_1493 | Cla_0926 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | 0.416 |
| aroC | aroE | Cla_1493 | Cla_0492 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.891 |
| aroC | pabA | Cla_1493 | Cla_0985 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase component II, glutamine amidotransferase; Pfam match to PF00117.19 GATase. | 0.912 |
| aroC | pabB | Cla_1493 | Cla_0984 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase component I, ADC synthase; Pfam match to PF00425.9 Chorismate_bind. | 0.956 |
| aroC | pheA | Cla_1493 | Cla_1360 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.988 |
| aroC | trpB | Cla_1493 | Cla_1345 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.572 |
| aroE | Cla_0926 | Cla_0492 | Cla_0926 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS. | 0.478 |
| aroE | aroC | Cla_0492 | Cla_1493 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.891 |
| aroE | pabA | Cla_0492 | Cla_0985 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Para-aminobenzoate synthase component II, glutamine amidotransferase; Pfam match to PF00117.19 GATase. | 0.703 |