| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0842 | cmeC | Cla_0842 | Cla_1561 | Conserved hypothetical protein. | RND efflux system, outer membrane lipoprotein CmeC; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.751 |
| Cla_0842 | cmeD | Cla_0842 | Cla_0986 | Conserved hypothetical protein. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.748 |
| Cla_0842 | macB | Cla_0842 | Cla_0918 | Conserved hypothetical protein. | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.937 |
| Cla_0912 | Cla_1496 | Cla_0912 | Cla_1496 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.742 |
| Cla_0912 | cmeD | Cla_0912 | Cla_0986 | Conserved hypothetical protein. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.736 |
| Cla_0912 | holA | Cla_0912 | Cla_0950 | Conserved hypothetical protein. | Conserved hypothetical protein; Pfam match to PF06144.4 DNA_pol3_delta. | 0.765 |
| Cla_1496 | Cla_0912 | Cla_1496 | Cla_0912 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.742 |
| Cla_1496 | cmeD | Cla_1496 | Cla_0986 | Conserved hypothetical protein. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.752 |
| Cla_1496 | holA | Cla_1496 | Cla_0950 | Conserved hypothetical protein. | Conserved hypothetical protein; Pfam match to PF06144.4 DNA_pol3_delta. | 0.770 |
| cmeA | cmeB | Cla_1559 | Cla_1560 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | 0.999 |
| cmeA | cmeC | Cla_1559 | Cla_1561 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | RND efflux system, outer membrane lipoprotein CmeC; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.999 |
| cmeA | cmeD | Cla_1559 | Cla_0986 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.977 |
| cmeA | cmeE | Cla_1559 | Cla_0987 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Membrane fusion component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.713 |
| cmeA | cmeF | Cla_1559 | Cla_0988 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Integral membrane component of efflux system; Pfam match to PF00873.10 ACR_tran; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.932 |
| cmeA | macB | Cla_1559 | Cla_0918 | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.990 |
| cmeB | cmeA | Cla_1560 | Cla_1559 | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.999 |
| cmeB | cmeC | Cla_1560 | Cla_1561 | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | RND efflux system, outer membrane lipoprotein CmeC; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.999 |
| cmeB | cmeD | Cla_1560 | Cla_0986 | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. | 0.964 |
| cmeB | cmeE | Cla_1560 | Cla_0987 | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | Membrane fusion component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.915 |
| cmeB | cmeF | Cla_1560 | Cla_0988 | RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran. | Integral membrane component of efflux system; Pfam match to PF00873.10 ACR_tran; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.416 |