| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0248 | clpS | Cla_0248 | Cla_1062 | Conserved hypothetical protein, putative bacterioferritin; Pfam match to PF00210.15 Ferritin; Belongs to the Dps family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.856 |
| aat | clpA | Cla_1064 | Cla_1063 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | 0.856 |
| aat | clpS | Cla_1064 | Cla_1062 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.958 |
| aat | csrA | Cla_1064 | Cla_1058 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. | 0.759 |
| aat | ispE | Cla_1064 | Cla_1059 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Pfam match to PF00288.17 GHMP_kinases_N; Belongs to the GHMP kinase family. IspE subfamily. | 0.760 |
| aat | smpB | Cla_1064 | Cla_1060 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.790 |
| aat | truB | Cla_1064 | Cla_1057 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.759 |
| aat | trxC | Cla_1064 | Cla_1061 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Possible periplasmic thioredoxin; Pfam match to PF00085.11 Thioredoxin. | 0.825 |
| aat | uvrD | Cla_1064 | Cla_1056 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase. | 0.759 |
| clpA | aat | Cla_1063 | Cla_1064 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.856 |
| clpA | clpS | Cla_1063 | Cla_1062 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.976 |
| clpA | csrA | Cla_1063 | Cla_1058 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. | 0.772 |
| clpA | ispE | Cla_1063 | Cla_1059 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | Pfam match to PF00288.17 GHMP_kinases_N; Belongs to the GHMP kinase family. IspE subfamily. | 0.806 |
| clpA | smpB | Cla_1063 | Cla_1060 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.806 |
| clpA | truB | Cla_1063 | Cla_1057 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.827 |
| clpA | trxC | Cla_1063 | Cla_1061 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | Possible periplasmic thioredoxin; Pfam match to PF00085.11 Thioredoxin. | 0.836 |
| clpA | uvrD | Cla_1063 | Cla_1056 | ATP-dependent ClpAP protease, ATP-binding subunit ClpA; Pfam matches to PF00004.20 AAA, and to PF07724.5 AAA_2; Belongs to the ClpA/ClpB family. | ATP-dependent DNA helicase; Pfam match to PF00580.12 UvrD-helicase. | 0.805 |
| clpB | clpS | Cla_0711 | Cla_1062 | Protein disaggregating chaperone ClpB; Pfam matches to PF02861.11 Clp_N, and to PF00004.20 AAA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.795 |
| clpS | Cla_0248 | Cla_1062 | Cla_0248 | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | Conserved hypothetical protein, putative bacterioferritin; Pfam match to PF00210.15 Ferritin; Belongs to the Dps family. | 0.856 |
| clpS | aat | Cla_1062 | Cla_1064 | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.958 |
