STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (300 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.967
Cla_1565
Conserved hypothetical integral membrane protein (UPF0093 domain protein); Pfam match to PF03653.4 UPF0093.
 
  
 0.945
Cla_1070
Oxidoreductase, Gfo/Idh/MocA family; Pfam match to PF01408.13 GFO_IDH_MocA.
     
 0.828
Cla_1071
DegT/DnrJ/EryC1/StrS aminotransferase family enzyme; Pfam match to PF01041.8 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family.
       0.804
sodB
Superoxide dismutase (Fe); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
      
 0.662
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.617
maf
Septum formation protein Maf; Pfam match to PF02545.5 Maf; Belongs to the Maf family.
       0.617
pbpA
Penicillin-binding protein 1A; Pfam matches to PF00912.13 Transgly, and to PF00905.13 Transpeptidase.
       0.617
ccsBA
Cytochrome c biogenesis protein, CcmF/CycK/CcsA family; Pfam match to PF01578.11 Cytochrom_C_asm.
 
  
 0.576
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.568
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.