STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemNOxygen-independent coproporphyrinogen III oxidase; Pfam matches to PF04055.12 Radical_SAM, and to PF06969.7 HemN_C. (451 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.937
hemN1
Oxygen-independent coproporphyrinogen III oxidase HemN, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.922
Cla_1565
Conserved hypothetical integral membrane protein (UPF0093 domain protein); Pfam match to PF03653.4 UPF0093.
    
 0.906
hemB
Delta-aminolevulinic acid dehydratase; Pfam match to PF00490.12 ALAD; Belongs to the ALAD family.
     
 0.824
Cla_1130
Conserved hypothetical protein; Belongs to the UPF0763 family.
       0.804
Cla_1132
Conserved hypothetical protein, putative iron-sulfur-cluster binding protein; Pfam matches to PF02754.7 CCG, and to PF02754.7 CCG.
       0.804
ccoN
Cytochrome c oxidase, cbb3-type, subunit I; Pfam match to PF00115.11 COX1; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.794
ccoO
Cytochrome c oxidase, cbb3-type, subunit II; Pfam match to PF02433.6 FixO.
 
    0.752
ccoG
Putative ferredoxin-like protein.
 
  
 0.744
Cla_1126
Conserved hypothetical protein.
       0.627
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.