Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mapAOuter membrane liproprotein MapA. (215 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.895
ctsW
Conserved hypothetical protein, possible purine/pyrimidine phosphoribosyltransferase.
       0.825
cadF
Outer membrane fibronectin-binding protein; Pfam match to PF00691.11 OmpA.
      
 0.661
cjaC
Amino acid ABC transporter, permease/substrate-binding lipoprotein; Pfam match to PF00497.11 SBP_bac_3.
      
 0.654
flaA
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.652
ccoN
Cytochrome c oxidase, cbb3-type, subunit I; Pfam match to PF00115.11 COX1; Belongs to the heme-copper respiratory oxidase family.
      
 0.650
flgQ
Conserved hypothetical protein.
       0.625
flgP
Conserved hypothetical lipoprotein (DUF400 domain protein); Pfam match to PF04164.4 DUF400.
       0.625
flaB
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.598
Cla_1145
Conserved hypothetical protein, putative sodium/sulfate transporter; Pfam match to PF00939.10 Na_sulph_symp.
       0.594
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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