STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mapAOuter membrane liproprotein MapA. (215 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.868
ctsW
Conserved hypothetical protein, possible purine/pyrimidine phosphoribosyltransferase.
       0.804
flgQ
Conserved hypothetical protein.
       0.590
flgP
Conserved hypothetical lipoprotein (DUF400 domain protein); Pfam match to PF04164.4 DUF400.
       0.590
cadF
Outer membrane fibronectin-binding protein; Pfam match to PF00691.11 OmpA.
      
 0.566
cjaC
Amino acid ABC transporter, permease/substrate-binding lipoprotein; Pfam match to PF00497.11 SBP_bac_3.
      
 0.561
Cla_1145
Conserved hypothetical protein, putative sodium/sulfate transporter; Pfam match to PF00939.10 Na_sulph_symp.
       0.517
ccoN
Cytochrome c oxidase, cbb3-type, subunit I; Pfam match to PF00115.11 COX1; Belongs to the heme-copper respiratory oxidase family.
      
 0.465
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.444
cjaA
Amino acid ABC transporter, periplasmic solute-binding lipoprotein; Pfam match to PF00497.11 SBP_bac_3.
   
  
 0.434
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.