Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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Cla_1153Conserved hypothetical integral membrane protein, putative transporter, LysE family; Pfam match to PF01810.9 LysE. (197 aa)    
Predicted Functional Partners:
dapE
N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.825
npdA
Conserved hypothetical protein, putative NAD-dependent deacetylase; Pfam match to PF02146.8 SIR2.
       0.825
mutS
Mismatch repair ATPase MutS, MutS2 family; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.825
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
       0.824
Cla_1156
Conserved hypothetical protein.
       0.820
Cla_1158
Hydrolase, carbon-nitrogen family.
       0.773
Cla_1146
Thiamine-phosphate pyrophosphorylase/regulatory protein TenI, putative; Pfam match to PF02581.8 TMP-TENI.
  
    0.567
thiF
ThiS adenylation protein ThiF; Pfam match to PF00899.12 ThiF.
       0.563
thiS
Thiamine biosynthesis protein ThiS; Pfam match to PF02597.11 ThiS.
       0.562
thiG
Thiamine biosynthesis ThiGH complex, ThiG subunit; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.553
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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