STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutSMismatch repair ATPase MutS, MutS2 family; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (731 aa)    
Predicted Functional Partners:
dapE
N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.804
Cla_1153
Conserved hypothetical integral membrane protein, putative transporter, LysE family; Pfam match to PF01810.9 LysE.
       0.804
Cla_1156
Conserved hypothetical protein.
       0.804
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
       0.804
recJ
single-stranded-DNA specific exonuclease; Pfam matches to PF01368.11 DHH, and to PF02272.10 DHHA1.
 
   
 0.787
Cla_1158
Hydrolase, carbon-nitrogen family.
       0.787
npdA
Conserved hypothetical protein, putative NAD-dependent deacetylase; Pfam match to PF02146.8 SIR2.
       0.783
Cla_1538
NFACT-R_1 domain-containing protein; Pfam match to PF05670.4 DUF814.
 
     0.752
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
   0.746
cysQ
3'(2'),5'-bisphosphate nucleotidase; Pfam match to PF00459.16 Inositol_P.
      
 0.605
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.