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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (524 aa)    
Predicted Functional Partners:
pycB
Pyruvate carboxylase, subunit B; Pfam matches to PF00682.10 HMGL-like, and to PF00364.13 Biotin_lipoyl.
    
 0.990
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.924
mdh
Malate dehydrogenase; Pfam matches to PF00056.14 Ldh_1_N, and to PF02866.9 Ldh_1_C; Belongs to the LDH/MDH superfamily.
   
 
 0.924
pyk
Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family.
     
 0.923
aspA
Aspartate ammonia-lyase; Pfam match to PF00206.11 Lyase_1.
   
 
 0.917
por
Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR.
  
 
 0.914
mqo
Malate:quinone oxidoreductase; Pfam match to PF01266.15 DAO.
    
 0.912
pycA
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.902
gdhA
Glutamate dehydrogenase; Pfam matches to PF02812.9 ELFV_dehydrog_N, and to PF00208.12 ELFV_dehydrog; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.839
argH
Pfam match to PF00206.11 Lyase_1.
  
 
  0.834
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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