Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cla_1212Conserved hypothetical lipoprotein; Pfam match to PF00578.12 AhpC-TSA. (181 aa)    
Predicted Functional Partners:
ftsY
Signal recognition particle-docking GTPase FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
  
 
 0.833
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.827
fliY
Flagellar motor switch protein FliY; Pfam match to PF01052.11 SpoA.
    
   0.805
Cla_1209
Conserved hypothetical protein, FAD-binding domain protein.
       0.773
Cla_0809
Cytochrome c biogenesis protein; Pfam match to PF01578.11 Cytochrom_C_asm.
  
  
 0.718
ccsBA
Cytochrome c biogenesis protein, CcmF/CycK/CcsA family; Pfam match to PF01578.11 Cytochrom_C_asm.
  
  
 0.718
atpB
ATP synthase F0 sector, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
   
   0.718
dsbD
Thiol:disulfide interchange protein DsbD; Pfam match to PF02683.6 DsbD.
  
 
 0.713
ahpC
Alkyl hydroperoxide reductase C22 protein, AhpC/TsaA family; Pfam match to PF00578.12 AhpC-TSA.
  
 0.692
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
 0.677
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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