STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Cla_1215Conserved hypothetical integral membrane protein; Pfam match to PF09335.2 SNARE_assoc. (187 aa)    
Predicted Functional Partners:
Cla_1213
Conserved hypothetical protein, 5-formyltetrahydrofolate cyclo-ligase family; Pfam match to PF01812.11 5-FTHF_cyc-lig; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.832
Cla_1216
Conserved hypothetical protein, putative ComEC/Rec2-related protein domain protein; Pfam match to PF03772.7 Competence.
       0.825
rny
Conserved hypothetical protein, HDIG/HD/KH domain protein; Endoribonuclease that initiates mRNA decay.
       0.821
ftsY
Signal recognition particle-docking GTPase FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
       0.656
Cla_1212
Conserved hypothetical lipoprotein; Pfam match to PF00578.12 AhpC-TSA.
       0.656
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.647
Cla_1209
Conserved hypothetical protein, FAD-binding domain protein.
  
    0.557
atpB
ATP synthase F0 sector, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
       0.462
flgC
Flagellar proximal rod protein FlgC; Pfam matches to PF00460.11 Flg_bb_rod, and to PF06429.4 DUF1078; Belongs to the flagella basal body rod proteins family.
   
   0.437
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
    0.433
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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