Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pglBOligosaccharide transferase to N-glycosylate proteins; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (GalNAc(2)GlcGalNAc(3)Bac(NAc)(2) in eubacteria, where Bac(NAc)(2) is di-N-acetyl bacillosamine) from the lipid carrier undecaprenol-pyrophosphate to an asparagine residue within an Asp/Glu-Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. (712 aa)    
Predicted Functional Partners:
pglA
GalNAc alpha-1,3-transferase; Pfam match to PF00534.11 Glycos_transf_1.
     
 0.959
pglD
UDP-4-amino-sugar N-acetyltransferase.
     
 0.959
pglC
Galactosyltransferase; Pfam match to PF02397.7 Bac_transf.
     
 0.942
pglF
UDP-GlcNAc C4,6 dehydratase; Pfam match to PF02719.6 Polysacc_synt_2.
     
 0.938
pglE
UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Pfam match to PF01041.8 DegT_DnrJ_EryC1; Belongs to the DegT/DnrJ/EryC1 family.
     
 0.937
pglK
ABC transporter, ATP-binding protein/permease, glycan transport; Pfam match to PF00005.18 ABC_tran.
   
 
 0.936
pglJ
GalNAc alpha-1,4-transferase; Pfam match to PF00534.11 Glycos_transf_1.
     
 0.927
pglH
GalNAc alpha-1,4-transferase; Pfam match to PF00534.11 Glycos_transf_1.
     
 0.904
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.895
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
  
   0.832
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.