Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
gdhAGlutamate dehydrogenase; Pfam matches to PF02812.9 ELFV_dehydrog_N, and to PF00208.12 ELFV_dehydrog; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (455 aa)    
Predicted Functional Partners:
putA
Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 0.974
nrfH
Cytochrome c nitrite reductase, small subunit NrfH.
   
 
 0.938
nrfA
Cytochrome c nitrite reductase, catalytic subunit NrfA; Pfam match to PF02335.6 Cytochrom_C552; Belongs to the cytochrome c-552 family.
     
 0.934
Cla_1158
Hydrolase, carbon-nitrogen family.
   
 
 0.927
glnA
Glutamine synthetase; Pfam matches to PF03951.10 Gln-synt_N, and to PF00120.15 Gln-synt_C; Belongs to the glutamine synthetase family.
   
 
 0.924
gltX2
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
    
 0.913
aspB
Aspartate aminotransferase; Pfam match to PF00155.12 Aminotran_1_2.
   
 
 0.911
purQ
Phosphoribosylformylglycinamidine synthase, PurQ subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
    
  0.905
mdh
Malate dehydrogenase; Pfam matches to PF00056.14 Ldh_1_N, and to PF02866.9 Ldh_1_C; Belongs to the LDH/MDH superfamily.
   
 
 0.864
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.850
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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