STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pseAPseudaminic acid biosynthesis protein PseA. (378 aa)    
Predicted Functional Partners:
hisF2
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
   0.914
hisH2
Imidazoleglycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
    0.861
ptmF
Flagellin modification protein PtmF.
 
    0.605
Cla_1329
Conserved hypothetical integral membrane protein (DUF81 domain protein); Pfam match to PF01925.10 DUF81.
       0.553
hisB
Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Pfam matches to PF08645.2 PNK3P, and to PF00475.9 IGPD; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
 
  0.533
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.527
thiS
Thiamine biosynthesis protein ThiS; Pfam match to PF02597.11 ThiS.
  
   0.518
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Pfam match to PF00977.12 His_biosynth.
     
  0.499
metS
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.480
ptmD
Flagellin modification protein PtmD, putative UDP-N-acetylglucosamine 2-epimerase; Pfam match to PF02350.10 Epimerase_2.
 
  
 0.466
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.