STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (391 aa)    
Predicted Functional Partners:
Cla_0926
Conserved hypothetical protein, putative indole-3-glycerol phosphate synthase; Pfam match to PF00218.12 IGPS.
 
 
 0.994
pabB
Para-aminobenzoate synthase component I, ADC synthase; Pfam match to PF00425.9 Chorismate_bind.
 
  
 0.975
pabA
Para-aminobenzoate synthase component II, glutamine amidotransferase; Pfam match to PF00117.19 GATase.
 
  
 0.958
ilvA
Threonine dehydratase; Pfam match to PF00291.16 PALP.
   
0.935
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.923
serB
3-phosphoserine phosphatase; Pfam match to PF00702.17 Hydrolase.
   
 
 0.913
sdaA
L-serine dehydratase; Pfam matches to PF03315.6 SDH_beta, and to PF03313.6 SDH_alpha; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Pfam match to PF01066.12 CDP-OH_P_transf; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
Cla_1145
Conserved hypothetical protein, putative sodium/sulfate transporter; Pfam match to PF00939.10 Na_sulph_symp.
 
      0.856
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.851
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.