STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
cdtBCytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. (259 aa)    
Predicted Functional Partners:
cdtA
Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins.
   
 
 0.991
cdtC
Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA.
     
 0.965
cadF
Outer membrane fibronectin-binding protein; Pfam match to PF00691.11 OmpA.
   
  
 0.880
ciaB
Invasion antigen B.
      
 0.811
csdA
Conserved hypothetical protein, putative NifS-like aminotransferase; Pfam match to PF00266.10 Aminotran_5.
    
   0.797
racR
Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C.
      
 0.693
dnaJ
Co-chaperone and heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...]
      
 0.681
gyrA
DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.676
flaA
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
   
  
 0.661
flaB
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
   
  
 0.661
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.