| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdtA | cdtB | Cla_1376 | Cla_1375 | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | 0.994 |
| cdtA | cdtC | Cla_1376 | Cla_1374 | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | 0.973 |
| cdtA | pepT | Cla_1376 | Cla_1377 | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.547 |
| cdtA | pheA | Cla_1376 | Cla_1360 | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.416 |
| cdtB | cdtA | Cla_1375 | Cla_1376 | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | 0.994 |
| cdtB | cdtC | Cla_1375 | Cla_1374 | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | 0.970 |
| cdtB | pepT | Cla_1375 | Cla_1377 | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.505 |
| cdtB | pheA | Cla_1375 | Cla_1360 | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.543 |
| cdtC | cdtA | Cla_1374 | Cla_1376 | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | 0.973 |
| cdtC | cdtB | Cla_1374 | Cla_1375 | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | 0.970 |
| cdtC | pepT | Cla_1374 | Cla_1377 | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.505 |
| cdtC | pheA | Cla_1374 | Cla_1360 | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.452 |
| glyA | pepT | Cla_0489 | Cla_1377 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.843 |
| glyA | pheA | Cla_0489 | Cla_1360 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.418 |
| glyA | por | Cla_0489 | Cla_0388 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR. | 0.626 |
| pepT | cdtA | Cla_1377 | Cla_1376 | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Cytolethal distending toxin, subunit CdtA; CDTs are cytotoxins. | 0.547 |
| pepT | cdtB | Cla_1377 | Cla_1375 | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Cytolethal distending toxin, subunit CdtB; Possible pseudogene; Pfam match to PF03372.14 Exo_endo_phos. | 0.505 |
| pepT | cdtC | Cla_1377 | Cla_1374 | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Cytolethal distending toxin, subunit CdtC; Pfam match to PF03498.5 CDtoxinA. | 0.505 |
| pepT | glyA | Cla_1377 | Cla_0489 | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.843 |
| pepT | pheA | Cla_1377 | Cla_1360 | Peptidase T, M20 family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.426 |