| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0322 | bioC | Cla_0322 | Cla_1385 | Cytochrome P450 family protein; Pfam match to PF00067.13 p450; Belongs to the cytochrome P450 family. | Biotin synthesis protein BioC. | 0.415 |
| Cla_0322 | pheA | Cla_0322 | Cla_1360 | Cytochrome P450 family protein; Pfam match to PF00067.13 p450; Belongs to the cytochrome P450 family. | Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT. | 0.402 |
| Cla_1386 | Cla_1388 | Cla_1386 | Cla_1388 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | 0.804 |
| Cla_1386 | bioA | Cla_1386 | Cla_1389 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.721 |
| Cla_1386 | bioB | Cla_1386 | Cla_0160 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.403 |
| Cla_1386 | bioC | Cla_1386 | Cla_1385 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Biotin synthesis protein BioC. | 0.947 |
| Cla_1386 | bioD | Cla_1386 | Cla_1390 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.550 |
| Cla_1386 | bioF | Cla_1386 | Cla_1387 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2. | 0.989 |
| Cla_1388 | Cla_1386 | Cla_1388 | Cla_1386 | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 0.804 |
| Cla_1388 | bioA | Cla_1388 | Cla_1389 | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.561 |
| Cla_1388 | bioC | Cla_1388 | Cla_1385 | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | Biotin synthesis protein BioC. | 0.784 |
| Cla_1388 | bioF | Cla_1388 | Cla_1387 | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | 8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2. | 0.804 |
| bioA | Cla_1386 | Cla_1389 | Cla_1386 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 0.721 |
| bioA | Cla_1388 | Cla_1389 | Cla_1388 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. | 0.561 |
| bioA | bioB | Cla_1389 | Cla_0160 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.990 |
| bioA | bioC | Cla_1389 | Cla_1385 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthesis protein BioC. | 0.803 |
| bioA | bioD | Cla_1389 | Cla_1390 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.996 |
| bioA | bioF | Cla_1389 | Cla_1387 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2. | 0.994 |
| bioB | Cla_1386 | Cla_0160 | Cla_1386 | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 0.403 |
| bioB | bioA | Cla_0160 | Cla_1389 | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.990 |