| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0636 | bioB | Cla_0636 | Cla_0160 | Putative hydrolase, alpha/beta fold family; Pfam match to PF00561.11 Abhydrolase_1. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.468 |
| Cla_0636 | bioD | Cla_0636 | Cla_1390 | Putative hydrolase, alpha/beta fold family; Pfam match to PF00561.11 Abhydrolase_1. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.427 |
| Cla_0636 | bioF | Cla_0636 | Cla_1387 | Putative hydrolase, alpha/beta fold family; Pfam match to PF00561.11 Abhydrolase_1. | 8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2. | 0.448 |
| Cla_0636 | ribD | Cla_0636 | Cla_0227 | Putative hydrolase, alpha/beta fold family; Pfam match to PF00561.11 Abhydrolase_1. | Riboflavin biosynthesis protein; Pfam match to PF00383.13 dCMP_cyt_deam_1. | 0.484 |
| Cla_1386 | bioA | Cla_1386 | Cla_1389 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.721 |
| Cla_1386 | bioB | Cla_1386 | Cla_0160 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.403 |
| Cla_1386 | bioC | Cla_1386 | Cla_1385 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Biotin synthesis protein BioC. | 0.947 |
| Cla_1386 | bioD | Cla_1386 | Cla_1390 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.550 |
| Cla_1386 | bioF | Cla_1386 | Cla_1387 | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2. | 0.989 |
| Cla_1391 | Cla_1392 | Cla_1391 | Cla_1392 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | 0.954 |
| Cla_1391 | ansB | Cla_1391 | Cla_1393 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | L-asparaginase; Pfam match to PF01112.9 Asparaginase_2. | 0.528 |
| Cla_1391 | bioD | Cla_1391 | Cla_1390 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.804 |
| Cla_1392 | Cla_1391 | Cla_1392 | Cla_1391 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | 0.954 |
| Cla_1392 | ansB | Cla_1392 | Cla_1393 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | L-asparaginase; Pfam match to PF01112.9 Asparaginase_2. | 0.538 |
| Cla_1392 | bioD | Cla_1392 | Cla_1390 | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.804 |
| ansB | Cla_1391 | Cla_1393 | Cla_1391 | L-asparaginase; Pfam match to PF01112.9 Asparaginase_2. | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | 0.528 |
| ansB | Cla_1392 | Cla_1393 | Cla_1392 | L-asparaginase; Pfam match to PF01112.9 Asparaginase_2. | Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res. | 0.538 |
| ansB | bioD | Cla_1393 | Cla_1390 | L-asparaginase; Pfam match to PF01112.9 Asparaginase_2. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.554 |
| bioA | Cla_1386 | Cla_1389 | Cla_1386 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452. | 0.721 |
| bioA | bioB | Cla_1389 | Cla_0160 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.990 |