Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (190 aa)    
Predicted Functional Partners:
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
 
 0.997
bioA
Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Pfam match to PF00202.12 Aminotran_3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.997
bioF
8-amino-7-oxononanoate synthase; Pfam match to PF00155.12 Aminotran_1_2.
 
  
 0.972
Cla_1391
Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res.
       0.825
Cla_1392
Putative multidrug resistance protein, SMR family; Pfam match to PF00893.10 Multi_Drug_Res.
       0.825
bioC
Biotin synthesis protein BioC.
 
  
 0.753
ansB
L-asparaginase; Pfam match to PF01112.9 Asparaginase_2.
       0.620
Cla_1386
Conserved hypothetical protein (DUF452 domain protein); Pfam match to PF04301.4 DUF452.
 
    0.578
pheA
Chorismate mutase/prephenate dehydratase; Pfam matches to PF01817.12 CM_2, and to PF00800.9 PDT.
     
 0.463
Cla_0636
Putative hydrolase, alpha/beta fold family; Pfam match to PF00561.11 Abhydrolase_1.
  
  
 0.421
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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