Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mreCRod shape-determining protein MreC. (246 aa)    
Predicted Functional Partners:
mreB
Rod shape-determining protein MreB; Pfam match to PF06723.4 MreB_Mbl.
  
 
 0.990
pbpC
Penicillin-binding protein 2; Pfam matches to PF03717.6 PBP_dimer, and to PF00905.13 Transpeptidase.
 
 
 0.906
clpX
ATP-dependent ClpXP protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
     
 0.852
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
       0.825
fabZ
3-hydroxymyristoyl-(acyl carrier protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
       0.825
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.800
lolA
Outer membrane lipoprotein carrier protein, LolA family; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
   
 0.794
Cla_0695
TrkA domain protein; Pfam match to PF02080.12 TrkA_C.
  
     0.770
ctsW
Conserved hypothetical protein, possible purine/pyrimidine phosphoribosyltransferase.
 
     0.762
pbpA
Penicillin-binding protein 1A; Pfam matches to PF00912.13 Transgly, and to PF00905.13 Transpeptidase.
   
 
 0.754
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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