Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
homHomoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. (417 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.993
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.968
thrC
Threonine synthase; Pfam match to PF00291.16 PALP.
 
 
 0.965
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.923
lysC
Aspartate kinase; Pfam matches to PF00696.19 AA_kinase, and to PF01842.16 ACT; Belongs to the aspartokinase family.
 
 0.907
metC
Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP.
  
 
 0.884
aspC
Aminotransferase (AspC family); Pfam match to PF00155.12 Aminotran_1_2.
  
 
 0.861
ilvE
Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.848
Cla_1413
Conserved hypothetical protein (UPF0102 domain protein); Pfam match to PF02021.8 UPF0102; Belongs to the UPF0102 family.
       0.825
cysE
Serine O-acetyltransferase.
     
 0.821
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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