Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Cla_1418Conserved hypothetical protein, probable rRNA methyltransferase, TrmH family; Pfam matches to PF08032.3 SpoU_sub_bind, and to PF00588.10 SpoU_methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (226 aa)    
Predicted Functional Partners:
rsfS
Conserved hypothetical protein (DUF143 domain protein); Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
 
 0.854
rplC
Pfam match to PF00297.13 Ribosomal_L3.
 
 
 
 0.853
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.850
Cla_1416
Conserved hypothetical protein.
     
 0.842
Cla_1419
Tetrapyrrole methylase family protein; Pfam match to PF00590.11 TP_methylase.
     
 0.827
Cla_1417
Conserved hypothetical integral membrane protein.
       0.825
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.818
rplQ
Pfam match to PF01196.10 Ribosomal_L17.
  
   0.812
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 
 0.812
Cla_1413
Conserved hypothetical protein (UPF0102 domain protein); Pfam match to PF02021.8 UPF0102; Belongs to the UPF0102 family.
       0.812
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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