STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cla_1456Conserved hypothetical integral membrane protein. (496 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.816
Cla_1457
Type IIS restriction/modification enzyme; Fusion of CJ0031 and CJ0032.
       0.774
mltD
Peptidoglycan-binding LysM:Lytic transglycosylase, catalytic (SLT family); Pfam matches to PF01464.11 SLT, and to PF01476.11 LysM.
   
 
 0.615
torC
Trimethylamine N-oxide reductase, cytochrome c-type subunit.
       0.495
torA
Trimethylamine N-oxide reductase, catalytic subunit; Pfam matches to PF00384.13 Molybdopterin, and to PF01568.12 Molydop_binding; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.495
Cla_0420
TPR-domain containing protein; Pfam matches to PF00515.19 TPR_1, and to PF00515.19 TPR_1.
  
  
 0.459
Cla_0911
Chemotaxis protein MotB, putative; Pfam match to PF00691.11 OmpA.
  
 
 0.434
lldG
Conserved hypothetical protein (DUF162 domain protein); Pfam match to PF02589.6 DUF162.
       0.413
lldF
Putative iron-sulfur cluster binding protein; Pfam match to PF02589.6 DUF162.
       0.413
lldE
Cysteine-rich domain protein; Pfam matches to PF02754.7 CCG, and to PF02754.7 CCG.
       0.413
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.