Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folEPfam match to PF01227.13 GTP_cyclohydroI. (190 aa)    
Predicted Functional Partners:
queD
Conserved hypothetical protein, putative 6-pyruvoyl tetrahydropterin synthase.
  
 
 0.971
folP
Dihydropteroate synthase; Pfam match to PF00809.13 Pterin_bind.
  
 0.964
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family.
  
 
 0.937
ribA
GTP cyclohydrolase II; Pfam match to PF00925.11 GTP_cyclohydro2.
   
 
 0.933
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam match to PF01288.11 HPPK.
 
  
 0.930
Cla_1001
Conserved hypothetical protein (NIF3 domain protein); Pfam match to PF01784.9 NIF3.
    
 0.913
folB
Dihydroneopterin aldolase.
  
  
 0.912
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
 0.904
fliI
Flagellum-specific ATP synthase FliI; Pfam match to PF00006.16 ATP-synt_ab.
       0.825
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
  0.820
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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