STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmeCRND efflux system, outer membrane lipoprotein CmeC; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP. (480 aa)    
Predicted Functional Partners:
cmeA
RND efflux system, membrane fusion protein CmeA; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.999
cmeB
RND efflux system, inner membrane transporter CmeB; Pfam match to PF00873.10 ACR_tran.
 0.999
cmeD
Outer membrane component of efflux system; Pfam matches to PF02321.9 OEP, and to PF02321.9 OEP.
     
 0.974
macB
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.953
cmeR
Transcriptional regulator, TetR family; Pfam match to PF00440.14 TetR_N.
 
   
 0.945
cmeF
Integral membrane component of efflux system; Pfam match to PF00873.10 ACR_tran; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.826
cmeE
Membrane fusion component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.790
macA
AcrA/AcrE family efflux protein; Pfam match to PF00529.11 HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.761
Cla_0842
Conserved hypothetical protein.
  
 
 0.751
ccoG
Putative ferredoxin-like protein.
       0.622
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.