Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemN3Pfam match to PF04055.12 Radical_SAM. (443 aa)    
Predicted Functional Partners:
Cla_1562
Hypothetical protein.
       0.653
rlmN
Conserved hypothetical protein, radical SAM enzyme (Cfr family); Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
     0.601
Cla_1564
Conserved hypothetical protein, possible methyltransferase; Pfam match to PF08241.3 Methyltransf_11.
       0.596
Cla_0337
Conserved hypothetical protein, predicted ATP/GTP-binding protein.
  
     0.564
por
Pyruvate ferredoxin/flavodoxin oxidoreductase; Pfam matches to PF01855.10 POR_N, and to PF01558.9 POR.
  
  
 0.515
ccoN
Cytochrome c oxidase, cbb3-type, subunit I; Pfam match to PF00115.11 COX1; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.494
Cla_0336
Conserved hypothetical protein, predicted ATP/GTP-binding protein; Pfam match to PF00350.14 Dynamin_N.
  
     0.481
ccoG
Putative ferredoxin-like protein.
  
  
 0.481
ccoO
Cytochrome c oxidase, cbb3-type, subunit II; Pfam match to PF02433.6 FixO.
  
    0.469
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.415
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
Server load: low (10%) [HD]