STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP25978.1hydroxymethylglutaryl-CoA synthase. (389 aa)    
Predicted Functional Partners:
SFP25905.1
hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.998
SFP26007.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.995
SFP48169.1
Diphosphomevalonate decarboxylase.
 
 
 0.936
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.923
SFP48195.1
Mevalonate kinase.
 
 
 0.912
SFP48144.1
Phosphomevalonate kinase.
 
 
 0.911
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.867
SFP47564.1
Phytoene synthase.
   
 
 0.725
SFP73948.1
acetyl-CoA synthetase.
   
 
 0.702
SFP36372.1
3-oxoacyl-[acyl-carrier-protein] synthase II/nodulation protein E; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.675
Your Current Organism:
Halolactibacillus halophilus
NCBI taxonomy Id: 306540
Other names: DSM 17073, H. halophilus, Halolactibacillus halophilus Ishikawa et al. 2005, Halolactobacillus halophilus, IAM 15242, JCM 21694, NBRC 100868, NRIC 0628, strain M2-2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.