STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP43615.1Uncharacterized protein, YigZ family. (210 aa)    
Predicted Functional Partners:
tdk
Thymidine kinase.
 
  
  0.645
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.630
gcvH
Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
    
  0.571
SFO95928.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.551
SFP16495.1
Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.551
SFP29460.1
Dihydrolipoamide dehydrogenase.
   
 
  0.544
SFP67519.1
Dihydrolipoamide dehydrogenase.
   
 
  0.544
SFO91381.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.491
SFO88246.1
tRNA (adenine22-N1)-methyltransferase.
   
    0.407
SFO91859.1
Dimeric dUTPase, all-alpha-NTP-PPase (MazG) superfamily.
    
  0.403
Your Current Organism:
Halolactibacillus halophilus
NCBI taxonomy Id: 306540
Other names: DSM 17073, H. halophilus, Halolactibacillus halophilus Ishikawa et al. 2005, Halolactobacillus halophilus, IAM 15242, JCM 21694, NBRC 100868, NRIC 0628, strain M2-2
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