node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFP34052.1 | SFP60819.1 | SAMN05421839_11517 | SAMN05421839_13316 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Anthranilate synthase component 2. | 0.999 |
SFP34052.1 | guaA | SAMN05421839_11517 | SAMN05421839_12433 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.651 |
SFP34052.1 | ilvA | SAMN05421839_11517 | SAMN05421839_10913 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.796 |
SFP34052.1 | lgt | SAMN05421839_11517 | SAMN05421839_11519 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Phosphatidylglycerol:prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.534 |
SFP34052.1 | trpA | SAMN05421839_11517 | SAMN05421839_13321 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.948 |
SFP34052.1 | trpB | SAMN05421839_11517 | SAMN05421839_13320 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.926 |
SFP34052.1 | trpC | SAMN05421839_11517 | SAMN05421839_13318 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.995 |
SFP34052.1 | trpD | SAMN05421839_11517 | SAMN05421839_13317 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
SFP34052.1 | trpE | SAMN05421839_11517 | SAMN05421839_13315 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.666 |
SFP34052.1 | trpF | SAMN05421839_11517 | SAMN05421839_13319 | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.957 |
SFP60819.1 | SFP34052.1 | SAMN05421839_13316 | SAMN05421839_11517 | Anthranilate synthase component 2. | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | 0.999 |
SFP60819.1 | guaA | SAMN05421839_13316 | SAMN05421839_12433 | Anthranilate synthase component 2. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.715 |
SFP60819.1 | ilvA | SAMN05421839_13316 | SAMN05421839_10913 | Anthranilate synthase component 2. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.495 |
SFP60819.1 | trpA | SAMN05421839_13316 | SAMN05421839_13321 | Anthranilate synthase component 2. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
SFP60819.1 | trpB | SAMN05421839_13316 | SAMN05421839_13320 | Anthranilate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
SFP60819.1 | trpC | SAMN05421839_13316 | SAMN05421839_13318 | Anthranilate synthase component 2. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SFP60819.1 | trpD | SAMN05421839_13316 | SAMN05421839_13317 | Anthranilate synthase component 2. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SFP60819.1 | trpE | SAMN05421839_13316 | SAMN05421839_13315 | Anthranilate synthase component 2. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
SFP60819.1 | trpF | SAMN05421839_13316 | SAMN05421839_13319 | Anthranilate synthase component 2. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.999 |
guaA | SFP34052.1 | SAMN05421839_12433 | SAMN05421839_11517 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase. | 0.651 |