node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFS63217.1 | dnaJ | SAMN05421668_10649 | SAMN05421668_102111 | Nitrogen fixation protein NifU. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.494 |
SFS63217.1 | dnaK | SAMN05421668_10649 | SAMN05421668_102110 | Nitrogen fixation protein NifU. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.921 |
SFS85382.1 | SFT00485.1 | SAMN05421668_11335 | SAMN05421668_12617 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.519 |
SFS85382.1 | dnaJ | SAMN05421668_11335 | SAMN05421668_102111 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.882 |
SFS85382.1 | dnaK | SAMN05421668_11335 | SAMN05421668_102110 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.943 |
SFS85382.1 | groL | SAMN05421668_11335 | SAMN05421668_11843 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.652 |
SFS85382.1 | grpE | SAMN05421668_11335 | SAMN05421668_102109 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.801 |
SFS85382.1 | hrcA | SAMN05421668_11335 | SAMN05421668_102108 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.583 |
SFS85382.1 | htpG | SAMN05421668_11335 | SAMN05421668_11213 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.748 |
SFS91198.1 | SFT00485.1 | SAMN05421668_1178 | SAMN05421668_12617 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.519 |
SFS91198.1 | dnaJ | SAMN05421668_1178 | SAMN05421668_102111 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.882 |
SFS91198.1 | dnaK | SAMN05421668_1178 | SAMN05421668_102110 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.943 |
SFS91198.1 | groL | SAMN05421668_1178 | SAMN05421668_11843 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.652 |
SFS91198.1 | grpE | SAMN05421668_1178 | SAMN05421668_102109 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.801 |
SFS91198.1 | hrcA | SAMN05421668_1178 | SAMN05421668_102108 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.583 |
SFS91198.1 | htpG | SAMN05421668_1178 | SAMN05421668_11213 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.748 |
SFT00485.1 | SFS85382.1 | SAMN05421668_12617 | SAMN05421668_11335 | Hypothetical protein. | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | 0.519 |
SFT00485.1 | SFS91198.1 | SAMN05421668_12617 | SAMN05421668_1178 | Hypothetical protein. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.519 |
SFT00485.1 | dnaJ | SAMN05421668_12617 | SAMN05421668_102111 | Hypothetical protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.989 |
SFT00485.1 | dnaK | SAMN05421668_12617 | SAMN05421668_102110 | Hypothetical protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |